Lactoferrin, 60x250mg, 5pack: NZ Natural Health for New Zealand natural health products


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Lactoferrin, 60x250mg, 5pack

$157.27NZD

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Lactoferrin, 60x250mg, 5pack

$157.27NZD per unit

About This Product

Lactoferrin
Lactoferrin, natural antiviral, antifungal and antibacterial agent, manufactured from milk protein from New Zealand's antibiotic free, BSE free, pasture fed, out door herds, supplied direct from New Zealand at lowest prices - free airmail anywhere and no minimum order.
Lactoferrin plays several biological roles related to its iron binding ability immune support and antioxidant activities. Lactoferrin prevents the growth of pathogens, has anti bacterial, anti fungal, and anti viral activity, controls cell tissue damage caused by oxidation and also facilitates iron transportation. Bacterial, viral and fungal infections are dependent on a supply of free iron for reproduction and survival. Lactoferrin binds the free iron and reduces the amount of oxidative free radicals released during the inflammation process.
Lactoferrin promotes intestinal health by scavenging iron and balancing healthy flora in the G.I. tract. By modulating healthy levels of iron in the body, Lactoferrin plays a key role in maintaining overall health. Some in vitro studies suggest that lactoferrin acts synergistically with antifungal agents.

Description
Lactoferrin is a glycoprotein that belongs to the iron transporter or transferrin family. It was originally isolated from bovine milk, where it is found as a minor protein component of whey proteins (see Whey Proteins). Lactoferrin contains 703 amino acids and has a molecular weight of 80 kilodaltons. In addition to its presence in milk, it is also found in exocrine secretions of mammals and is released from neutrophil granules during inflammation.
Lactoferrin is considered a multifunctional or multi-tasking protein. It appears to play several biological roles. Owing to its iron-binding properties, lactoferrin is thought to play a role in iron uptake by the intestinal mucosa of the suckling neonate. That is, it appears to be the source of iron for breast-fed infants. It also appears to have antibacterial, antiviral, antifungal, anti-inflammatory, antioxidant and immunomodulatory activities.

Three isoforms of lactoferrin have been isolated: lactoferrin-alpha, lactoferrin-beta and lactoferrin-gamma. Lactoferrin-beta and lactoferrin-gamma have RNase activity, whereas lactoferrin-alpha does not. Receptors for lactoferrin are found in monocytes, lymphocytes, neutrophils, intestinal tissue and on certain bacteria. Lactoferrin is abbreviated LF and Lf. Bovine lactoferrin is abbreviated bLF. Bovine lactoferrin, derived from whey proteins, is marketed as a nutritional supplement. Supplemental lactoferrin typically contains low amounts of iron.

How it works
The possible antibacterial activity of supplemental lactoferrin might be accounted for, in part, by its ability to strongly bind iron. Iron is essential to support the growth of pathogenic bacteria. Lactoferrin may also inhibit the attachment of bacteria to the intestinal wall. A breakdown product of lactoferrin is the peptide lactoferricin. Lactoferricin, classified as a bioactive peptide, may also have antibacterial, as well as antiviral, activity. The possible antiviral activity of supplemental lactoferrin may be due to its inhibition of virus-cell fusion and viral entry into cells.
A few mechanisms are proposed for lactoferrin's possible immunomodulatory activity. Lactoferrin may promote the growth and differentiation of T lymphocytes. Lactoferrin appears to bind uniquely in the region of major histocompatability (MHC) proteins and the CD4 and CD8 determinants on T4 (helper) and T8 (suppressor) lymphocytes; it bears sequence homologies with the MHC Class II determinant. Lactoferrin also appears to play a role in the regulation of cytokines and lymphokines, such as tumor necrosis (TNF)-alpha and interleukin (IL)-6. Lactoferrin's possible antioxidant activity may also contribute to its possible immunomodulatory activity.
Lactoferrin's possible antioxidant activity can also be accounted for by its ability to strongly bind iron. Free iron is a major contributor to the generation of reactive oxygen species via the Fenton reaction. Lactoferrin's possible anti-inflammatory action may be accounted for by its possible antioxidant and immunomodulatory activities.

Suggested Usage Adults - Take 2 x 250mg capsules per day as a conditioning dose, one in the morning and one at night for a month or two then drop back to 1 x 250mg capsule per day.

This product was added to our catalog on Tuesday 04 November, 2008.

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